Foot ulcers are one of the main lower-extremity complications of diabetes mellitus. Diabetic neuropathy changes the structure of the foot, affecting its function and, consequently, resulting in increased plantar pressures. These pressures are a predictive risk factor for the development of diabetic foot ulcers. Therefore, it is important to implement strategies to protect the foot from abnormal biomechanical loading. This special session will address the biomechanical aspects of the diabetic foot complications, advances in biomechanical assessments and new approaches to the prevention and treatment of foot complications in patients with diabetes mellitus.